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Examples of nonsedating antidepressants include the monoamine oxidase inhibitor moclobemide, the selective serotonin reuptake inhibitors fluoxetine, paroxetine, and nefazodone, and the serotonin and norepinephrine uptake inhibitor (SNRI) venlafaxine.
The effect of antidepressants on driving behavior was assessed with the standard deviation of lateral position (SDLP) test.
However, there are other classes such as: atypical antidepressants, tricyclic antidepressants, and MAOIs that are typically used if a person doesn’t respond to the newer classes of drugs.
Included below is a comprehensive list of antidepressants that are currently available for clinical use throughout worldwide markets.
Analytical epidemiological studies, using predominantly older drivers, have documented increased crash risks, with a relative risk of 2.3 Leveille, Buchner, Koepsell, Mc Closkey, Wolf, and Gagner (1994).
A majority of antidepressants prescribed in the current era include: SSRIs and SNRIs.
The first drug in the SSRI class was Prozac (Fluoxetine), which hit the United States market in 1987. Luvox (Fluvoxamine maleate) was the next SSRI FDA approved in December 05, 1994.
However, now its marketing status is "Discontinued".
Celexa (Citalopram hydrobromide) was approved by the FDA in July 17, 1998.
Celexa is manufactured by Forest Pharmaceuticals, Inc.